Chest pain / Stable Angina

  • Assessment of endothelial function by non-invasive PAT
    predicts late cardiovascular adverse events
    Rubinstein et al, Eu Heart Journal (2010)

    • Method: 70 outpatients with unexplained chest pain
      (low-risk findings during stress testing and/or the absence of new obstructive lesions by an invasive coronary angiogram)
    • The patients were followed for CV adverse events (AE): death, myocardial infarction, revascularization or cardiac hospitalization) during a 7-year follow-up
    • Conclusion:  a low RH signal detected by EndoPAT®, consistent with endothelial dysfunction,
      was associated with higher AE (Adverse events)  rate. L_RHI was an independent predictor of AE.
    • Non-invasive assessment of peripheral vascular function may be useful for the identification of
      patients at risk for cardiac AEs.
    • Takeaway: PAT signal can be a valuable tool in assessing CVD risk in patients with unexplained
      chest pain, allowing timely treatment and prevention of adverse events.