Assessment of endothelial function by non-invasive PAT
predicts late cardiovascular adverse events
Rubinstein et al, Eu Heart Journal (2010)
Method: 70 outpatients with unexplained chest pain
(low-risk findings during stress testing and/or the absence of new obstructive lesions by an invasive coronary angiogram)
- The patients were followed for CV adverse events (AE): death, myocardial infarction, revascularization or cardiac hospitalization) during a 7-year follow-up
Conclusion: a low RH signal detected by EndoPAT®, consistent with endothelial dysfunction,
was associated with higher AE (Adverse events) rate. L_RHI was an independent predictor of AE.
Non-invasive assessment of peripheral vascular function may be useful for the identification of
patients at risk for cardiac AEs.
Takeaway: PAT signal can be a valuable tool in assessing CVD risk in patients with unexplained
chest pain, allowing timely treatment and prevention of adverse events.
- Method: 70 outpatients with unexplained chest pain