Digital Assessment of endothelial function and ischemic
heart disease in women
Matsuzawa et al, JACC 2010
Method: 140 chest pain postmenopausal women tested with EndoPAT®, coronary angiography for
obstructive CAD and if non obstructive or normal angiography – then tested with Acetylcholine
provocation test, adenosine reduced coronary flow reserve, and stress thallium test to further
diagnose ischemic heart disease.
Conclusion: PAT non-invasively predicted the presence of IHD, especially NOCAD
(non-obstructive) which cannot be diagnosed by anatomical tests (angiography).
PAT is a potentially useful clinical test and can effectively help to identify high-risk
women with chest pain.
- Method: 140 chest pain postmenopausal women tested with EndoPAT®, coronary angiography for