Endothelial dysfunction predicts residual risk in coronary
artery disease patients with statin therapy
Matsue et al, EU Heart Journal abstract suppl. 2013
Method: 213 CAD patients who were well treated with statin therapy (achieved LDL<100)
Patients were followed-up for secondary CAE for a median of 2.7 years.
During follow-up, CAE occurred in 6 (5.5%) patients in the L_RHI > 0.52 group and 16
(15.5%) patients in the L_RHI <0.52 group (P=0.023).
Conclusions: L_RHI (Endoscore) was an
independent predictor for CAE (coronary artery events) even after
adjusting by Framingham traditional risk factors for secondary CAE
Takeaway: EndoPAT® must be used to follow up on cad patients and target endothelial
function to improveprognosis.
- Method: 213 CAD patients who were well treated with statin therapy (achieved LDL<100)